Progesterone Vaginal Extended-Release Gel belongs to a class of progestin medications that are commonly used clinically for progesterone supplementation therapy in assisted reproductive technology. The drug has the same effect as oral medications and progesterone injections. Since progesterone is a major substance in the development of the meconium tissue, it is an indispensable component in increasing the receptivity of the endometrium to the implantation of the pregnant egg, and it also serves to maintain the pregnancy after the fertilized egg has been implanted. In the case of insufficient progesterone, the drug can be used to supplement progesterone in time to be treated. However, the use of this drug can produce adverse reactions, such as allergic reactions, perineal pain, nausea, vomiting, joint pain, loss of libido and so on, it is recommended that the use of physician’s guidance.