Normal androgens will not shorten the life span of men, but abnormal hormone secretion can cause corresponding pathological changes. Androgens are produced by the testes, and their main function is to stimulate the development and maturation of male sex organs, maintain normal libido, and promote the development and maturation of spermatozoa, if normal secretion of androgens will not shorten the life expectancy of men. However, insufficient secretion of androgen may cause hypogonadism, decreased libido, erectile dysfunction, muscle weakness, physical strength, memory loss and other symptoms, middle-aged and elderly men will also appear osteoporosis and other manifestations; androgen secretion is excessive and accompanied by symptoms of reproductive discomforts, considering that it is caused by adrenal gland tumors or testicular tumors, which have a certain impact on the life expectancy of human beings. It is recommended that men with androgen abnormalities should have a comprehensive diagnosis by a professional doctor to avoid single symptom diagnosis. Abnormalities should go to the regular hospital in a timely manner, identify the cause of the disease and then treatment, in order to achieve early recovery.