Normally, a lymph node is shaped like a fava bean, about a few millimeters in size, full on one side and sunken on the other, with a lymphatic portal structure on the sunken side. If there are lesions, the shape and size may change. Lymph nodes are located throughout the body and are connected to each other by lymphatic vessels. The main functions of lymph nodes are to filter lymph, remove bacteria and foreign bodies, produce lymphocytes and antibodies, and are part of the immune system. Normally, lymph nodes are about a few millimeters in size, similar to the size of a small cherry. If the lymph nodes are attacked by disease-causing microorganisms such as bacteria or viruses, or if they are invaded by cancerous cells, there may be a change in the enlargement of the lymph nodes, i.e., both their shape and size may change. It evolves from oval to round, resulting in the disappearance of lymphatic gates, and the size of the lymph node may increase from a few millimeters to several centimeters. In addition, if the patient develops lesions such as systemic lupus erythematosus rheumatologicus, Langerhan’s histiocytosis, tuberculosis, and necrotizing proliferative lymphadenopathy, lymph node morphology and size may also change. Therefore, if changes in the size and shape of lymph nodes are found during ultrasound or other examinations, the cause and condition must be clarified before follow-up treatment.