Thyroid nodules of 26 millimeters are generally difficult to dissipate, and if there are compression symptoms, surgery is required. If the diameter of the thyroid nodule is more than 1cm, there is no way to make it go away with medication alone, and corresponding treatment measures can be taken according to the nature of the nodule. Pathologically confirmed benign thyroid nodules with no localized compression symptoms can be observed and reviewed regularly. Benign thyroid nodules with compression symptoms require surgery. If there is a high suspicion of malignancy or the pathologic results confirm a malignant nodule, surgical removal is required. The incidence of thyroid nodules is relatively high, and there are both solitary and multiple nodules. A solitary thyroid nodule may be a high-functioning thyroid tumor or a simple benign nodule, etc., which needs to be judged according to the test results. Most of the multiple thyroid nodules are benign, small in diameter and asymptomatic, and can be observed and reviewed regularly. Thyroid nodules of 26 millimeters in diameter are recommended to seek prompt medical attention and take early symptomatic treatment measures to avoid delaying the condition.