What are the causes of severe pregnancy vomiting at night? Generally speaking, pregnancy, especially the first pregnancy, often has significant pregnancy vomiting, but it occurs mostly in the morning and after meals. If the patient has a history of ulcers in the past, if she has a history of ulcers or severe pregnancy vomiting and has not undergone gastroscopy, she should go to the hospital for endoscopy to exclude gastroduodenal lesions, as ulcer disease is not uncommon during pregnancy. If you have any hepatobiliary disease, a simple biochemical examination and imaging ultrasound can also help diagnose and exclude it. It is also important to know if there are other diseases and similar symptoms in the past, and it is best to see a doctor in time, as this is a special time.