Night blindness is considered to be a disease in which people with normal daytime vision are unable to see at night or when they enter a dark room. There are many causes of night blindness, and retinitis pigmentosa is a common clinical condition, in which night blindness gradually appears in the early stage of the disease, because retinitis pigmentosa is caused by the abnormal function of photoreceptors, and the involvement of optic rod cells is more serious in the majority of the patients, so that the dark vision of the patients is obviously impaired. A funduscopic examination will reveal typical retinal osteoblast-like pigmentation changes, for which there is currently no effective treatment. There are also other causes of night blindness, such as corneal chondromalacia caused by vitamin A deficiency, congenital aniridia, and advanced glaucoma.