Most antihypertensive drugs have a lowering effect on both high and low pressure, there are no drugs that specifically lower pressure, but the following two types of drugs have a more significant effect on lowering pressure: First, beta-blockers, commonly used drugs are metoprolol extended-release tablets, bisoprolol, carvedilol, labetalol, etc. These drugs can slow down the heart rate, relatively prolong the diastolic period, more blood flow in the aorta to the periphery, which can cause diastolic pressure The diastolic blood flow to the periphery, which can cause a significant decrease in diastolic blood pressure. Second, calcium channel blockers, commonly used drugs are nifedipine controlled-release tablets, amlodipine, levamlodipine, diltiazem, etc. These drugs help to diastole the small peripheral arteries, reduce peripheral vascular resistance, the blood in the aorta flows more easily to the periphery during the diastolic period of the heart, and the amount of blood in the aorta is reduced, causing a significant decrease in diastolic blood pressure.