Parkinson’s disease, as a degenerative chronic disease of the nervous system, the main treatments at present are medication and surgery, and deep brain electrical stimulation surgery has brought the gospel to many Parkinson’s disease patients. However, there are still many Parkinson’s disease patients who have problems in how to choose the timing of the beginning of treatment. Prof. Wang explains that the solution to the problem of the timing of the beginning of treatment can be viewed from several aspects, because there are many constraints on the timing of Parkinson’s drug treatment. First of all, the patient’s age factor is very important, if the patient is very old, it is necessary to treat as early as possible, so that the patient’s quality of life to get a good improvement; if it is a young patient, it may be necessary to consider the adverse effects of long-term medication, will not bother the patient for a long time, and the young patient is really more prone to adverse effects after taking the medication, such as motor complications, so that the patient will have to consider the need to delay the Treatment. However, the patient’s degree of disease progression and occupational factors are also important. Younger patients, such as those in their forties or fifties, need to work normally, so they need to take their medication as early as possible to improve their quality of life and ability to work. Or some people have more pronounced shaking, which looks bad on the outside, and patients feel that their usual social life is affected, so they can start treatment earlier. Some patients can consider taking medication later if they think they are just moving slower and can overcome it. Elderly patients who are retired and don’t have many social activities can also delay treatment. These factors are all relative. Another important aspect is the degree of symptoms. Generally, if there is tremor, muscle tonus, slowed movement, etc., which affects work and life, then treatment can be started. All these factors have to be analyzed together, which is the core idea of individualized treatment.