Clinically there is no joint medication for vertebrobasilar insufficiency, but for different patients, take different medication, specific drugs include lipid-lowering drugs, anticoagulants, antiplatelet drugs, antihypertensive drugs, hypoglycemic drugs, such as simvastatin, clopidogrel, spironolactone, metformin and so on. 1. Lipid-lowering drugs: e.g. simvastatin, fenofibrate, etc. Lipid-lowering drugs can be used for insufficient blood supply to the vertebrobasilar artery caused by atherosclerosis. Patients may have adverse reactions such as malignant abdominal pain, diarrhea, itchy skin rash, dyspeptic dizziness. Patients who are allergic to lipid-lowering drugs are prohibited. 2. Anticoagulants, antiplatelet agents: such as clopidogrel, warfarin and so on. These drugs can prevent thrombosis, long-term use of these drugs can produce bleeding tendency, patients allergic to these drugs are prohibited. 3. Antihypertensive drugs: such as spironolactone, amphotericin, nifedipine and so on. Excessive dosage of these drugs can produce hypotension, and some produce allergic reactions, with patients experiencing itchy skin rashes. Patients with insufficient blood supply to the vertebral basilar artery and hypertension can use antihypertensive drugs to control their blood pressure at a normal level. 4. Antihyperglycemic drugs, such as metformin and insulin. Patients with insufficient blood supply to the vertebral basilar artery who have high blood glucose can use hypoglycemic drugs to control their blood glucose at a normal level. Patients should use hypoglycemic drugs according to the situation of blood glucose, too much drug can produce hypoglycemic attacks, patients may experience hunger, weakness, and serious life-threatening. People with allergies should use them with caution. Patients with vertebrobasilar cerebral insufficiency should be given a combination of drugs according to the situation. To use the drug under the guidance of the physician’s interview, pay attention to the adverse effects of the drug as well as contraindications.