The side of the big toe hurts when you touch it may be caused by ingrown nails, onychomycosis, gouty arthritis and so on. 1. ingrown nail: mainly caused by the nail curved growth and embedded in the soft tissue next to the nail, local redness, swelling and pain, can be applied locally antibiotic ointment, such as erythromycin, mupirocin, etc. for anti-inflammatory treatment. If an abscess is formed, it needs to be incised and drained. 2. Nail groin infection: it is an inflammation of the tissues around the nail. If the condition is mild, manifested as redness, swelling and pain when pressed, it can be treated with topical erythromycin ointment; in serious cases, it may be necessary to remove the nail, or incise and drain the abscess. 3. Gouty arthritis: mainly due to high purine and hyperuricemia caused by the disease, the condition of the acute stage can be taken non-steroidal anti-inflammatory drugs, such as ibuprofen, acetaminophen, and appropriate to take uric acid-lowering medications, such as allopurinol, phenylbrominone, and so on. When the patient appeared to the side of the big toe pain, it is recommended to timely medical treatment, in clear specific causes, and then in the physician’s guidance for targeted treatment, not blindly self-medication.