Soreness after sleeping may be caused by overwork, cold and osteoporosis, which can be relieved by proper rest, massage and medication. 1. Excessive fatigue: when in the high intensity of physical labor or exercise, the muscles of the whole body will be excessive fatigue, after a night’s sleep, there will be a general soreness, body weakness symptoms. You can choose to take a proper rest, with massage sore parts, can effectively relieve the symptoms of generalized pain. 2. Cold and flu: when sleeping, not covered with a good blanket leads to cold and flu, which causes cold and flu, when you get up, there may be symptoms of generalized pain, you can follow the doctor’s advice to choose to take medication for treatment, such as acetaminophen and so on. 3. Osteoporosis: a bone metabolism disease, mainly due to the decrease of bone formation, bone resorption increased, in the sleep up will appear after the symptoms of generalized pain, you can choose under the guidance of the doctor calcium carbonate, vitamin D and other drugs to relieve. If the symptoms continue to be unrelieved, you should go to the hospital in time, and standardize the treatment under the doctor’s guidance. The above drugs should be used according to the doctor’s instructions.