Periodontal abscess can take amoxicillin, but first need to determine the source of periodontal abscess, because in the treatment of periodontal disease, drug treatment is only an auxiliary therapeutic role, mainly through some periodontal means to deal with. If the clear diagnosis is a periodontal abscess, the first step needs to be the location of the abscess to cut rows, the abscess drainage out, and then through a certain amount of medication rinsing, the pus cavity rinsed out, and then appropriate some medication to assist in the treatment can be. Periodontal bacteria are mainly anaerobic bacteria, generally will consider amoxicillin and tinidazole or metronidazole combined use, especially in the periodontal abscess caused by some interstitial infections, need to use some medications to assist in the treatment, but such as minor periodontal abscess, can be resolved through basic treatment, the use of localized mouthwash, you can control the inflammation.