The common causes of pain on one side of throat caused by swallowing saliva include acute tonsillitis, foreign body in pharynx and hypopharyngeal cancer, etc. The treatment options include anti-inflammatory treatment, foreign body removal and surgical treatment. 1. Acute tonsillitis: it is often caused by B-hemolytic streptococcus infection, which will cause local redness, swelling, mucous membrane damage and even ulcers, and anti-inflammatory drugs (cefaclor, etc.) need to be applied to deal with the problem; in general, it is necessary to pay attention to drinking more water and paying attention to a light diet. 2. Foreign body in the pharynx: after eating food such as melon seeds or fish, it may lead to the retention of foreign body, which will cause related symptoms, and the symptoms can be relieved by removing the foreign body. 3. Hypopharyngeal cancer: more limited squamous cell carcinoma of hypopharynx can cause tingling in one side of the throat, which is often treated by radical resection of the lesion through surgery, combined with radiotherapy and chemotherapy. Stimulation by chemicals and trauma can also cause related symptoms, which need to be standardized under the guidance of clinicians. Swallowing saliva accompanied by pain on one side of the throat has more causative factors, it is recommended to actively consult a doctor to clarify the diagnosis and standardize the use of medication and treatment.