Running on an empty stomach in the morning is not recommended for bile reflux. Patients with bile reflux should try not to do strenuous exercise both at the onset and during treatment, because strenuous exercise may cause the bile reflux in the body to intensify and increase the damage to the stomach, thus aggravating the condition and causing unnecessary harm. Bile reflux in the late stage of treatment or after the end of treatment can be some light activities such as walking, after recovery can slowly develop a good habit of running, cycling and other exercise. Running on an empty stomach in the morning leads to increased bile reflux, bile will reflux into the stomach, harming the gastric mucosa will also occur heartburn and foreign body sensation in the throat. If these symptoms occur, it is necessary to go to the hospital in time for examination, improve the examination to clarify the cause of the disease, and then give targeted treatment or treatment, under the guidance of the doctor.