For children with high fever and sore throat, you can give them the following medications to relieve the condition: First, apply Qing Kai Ling pellets to children for treatment. If the symptoms of high fever and sore throat are caused by heat toxicity, most of the symptoms will be relieved after applying Qingkailing granules to children. Next, children should be given amoxicillin. If the cause of high fever and sore throat in children is due to purulent tonsillitis, the application of amoxicillin can kill the bacterial infection such as Streptococcus pneumoniae that causes purulent meningitis. Finally, children can be given timely application of macrolide antibiotics. If the high fever and sore throat are caused by Mycoplasma pneumoniae infection, apply macrolide antibiotics such as erythromycin and roxithromycin.