Moderate chronic non-atrophic inflammation of the gastric sinus with moderate intestinal epithelial hyperplasia is usually not completely curable, but the disease can be stabilized with treatment. Intestinal epithelial hyperplasia, mainly because the gastric mucosal epithelial cells are replaced by intestinal-type epithelial cells. It can be categorized into mild, moderate and severe according to its distribution degree, and is generally impossible to reverse. However, it can be helped by taking gastric mucosa protection drugs (such as aluminum thioglycollate, etc.) and gastric acid inhibiting drugs (such as omeprazole, etc.), which can help in controlling the condition and alleviating the uncomfortable symptoms. But for chronic gastro-sinusitis, as long as actively cooperate with the doctor’s treatment, to a large extent can be cured. In conclusion, if intestinal epithelial hyperplasia occurs, it must be treated actively to prevent further hyperplasia. Regularly review the condition and closely observe the changes in the condition.