Mixed hemorrhoid is a more serious disease, the harm is mainly as follows: 1, cause anal malfunction: if the disease is not cured for a long time, it will lead to defecation difficulties and anal incontinence; 2, mixed hemorrhoid infection: it will lead to serious sepsis, toxemia, septicemia; 3, because the anatomical location of the anus and vagina is close, hemorrhoid bleeding or inflammation will lead to gynecological inflammation; 4, lead to plant nerve disorders: cause pain in the back of the waist, thighs, etc.; 5, a large amount of mucus outflow, causing anal skin itching, serious cause skin eczema; 6, because rectal cancer and mixed hemorrhoid symptoms are close, it will cover up the diagnosis of rectal cancer, may lose the time of treatment.