Atrial fibrillation (atrial fibrillation) is the most common tachyarrhythmia. It is a serious risk to human health and life. The greatest risk to humans is the risk of cerebral infarction, known medically as a “stroke”. One third of the people who have a stroke have a history of atrial fibrillation. Therefore, stroke prevention is a priority for patients with atrial fibrillation. Currently, the main measure to prevent stroke in atrial fibrillation is still oral anticoagulants. Antiplatelet drugs such as aspirin have been tried in the past. However, clinical trials have found that these drugs have limited effect on stroke prevention, but increase the risk of bleeding. The most effective drug now is still warfarin. However, the therapeutic effect and risk of warfarin varies greatly among individuals and requires frequent blood sampling for coagulation indicators, otherwise there is a risk of major bleeding, especially brain bleeding. Thus, it is quite unchanged. In recent years, new oral anticoagulants have emerged one after another, which can provide the same anti-effect as warfarin without the need for frequent blood tests. Unfortunately, the cost is too high to make it widespread. Medical practitioners have been seeking easier and more effective ways to prevent stroke. Mechanistically, the occurrence of stroke is also inextricably linked to the structure of the heart. The heart is known to have 2 atria and 2 ventricles. In the anterolateral part of the atria, there is a structure that looks like an ear, called the “ear”. The auricle is anatomically a blind end that is connected to the body of the atrial cavity through a narrow neck. The pressure in the atrium itself is low, and the ear is a blind-ended structure, so blood flow in the ear is normally slow. When atrial fibrillation occurs, the entire atrium has completely lost its normal contraction function, and the blood flow in the heart ear is even slower and even tends to stagnate at this time. As we all know, running water does not rot, and the household pivot is not worm-eaten, so the possibility of blood clots forming from stagnant blood is very high. Once the thrombus is dislodged, it can spread to various organs with the blood flow. If a cerebral artery is embolized, it can lead to cerebral infarction (stroke). As you can see, the key to the formation of blood clots is the heart and ears. Medical doctors envisioned that if we managed to isolate the connection between the heart ear and the body of the atrium, then even if a thrombus formed in the heart ear, it would no longer be able to enter the atrium, and it would be much less likely to embolize the cerebral arteries. Inspired by the interventional treatment of congenital atrial septal defects or ventricular septal defects, they tried a blocking umbrella similar to the one used to treat atrial septal defects or ventricular septal defects to block the neck of the left heart ear, with apparent success in clinical trials. This procedure is known as left-ear occlusion. This method of “covering the heart’s ear” to prevent stroke has received increasing attention from international experts. Recently, this treatment has been introduced to China, and the instruments used have been gradually localized. The Tenth People’s Hospital of Tongji University has been in the leading position in basic and clinical research of atrial fibrillation in China, and has invested a lot of efforts in the localization and application of the left auricular blocker. At present, we have completed the clinical work of 59 cases of left auricular occlusion, and all of them have been successfully implanted without any serious complications. In the future, we will further strengthen the relevant clinical research in order to make this advanced method free more patients with atrial fibrillation from the threat of stroke as soon as possible.