The skull is one of the hardest bones in the human body and plays an important role in protecting brain tissue and maintaining normal intracranial pressure. However, there are some people who, for one reason or another, may suffer from cranial defects that pose a major threat to life and health. This is when cranial repair surgery is needed. The material used for skull repair is indeed very important, as it affects the outcome of the repair and the patient’s future life. Currently, titanium mesh is widely used in clinical practice, and newer PEEK materials are gradually being used. In fact, although the price of titanium mesh is low, but there are some disadvantages and complications, such as the patient’s postoperative sensitivity to hot and cold reactions, local chronic pain, more subcutaneous fluid; repair surgery, affecting the patient to receive CT, MRI and other medical examinations; chronic cutting ulcers, stress perforation to cranial repair failure; temporal fossa, zygomatic arch, brow frame and other irregular facial and cranial parts repair appearance cosmetic effect is poor, etc.. We use PEEK material to achieve ideal repair results. This material is three-dimensionally customized to restore the anatomical structure of the skull. In addition, this PEEK material is a polymer material that is highly compatible with the autologous skull and has comparable properties to the autologous skull in terms of elasticity, heat conduction, hardness, and stability, and will not interfere with medical examinations.