Quadrivalent is generally better than bivalent and is preferred when available. The bivalent is mainly for the two types of viruses that may cause cervical cancer, including HPV16 and 18 viral infections, while the quadrivalent HPV vaccine in addition to HPV16 and HPV18 can also prevent the two types of viruses that are prone to cause warts, including HPV6 and HPV11 viral infections. Warts are not cancerous, but a sexually transmitted disease characterized by wart-like lesions that also need to be prevented. The age for bivalent vaccination is 9 to 45 years old while the age for quadrivalent vaccination is 20 to 45 years old, and it is recommended to get the vaccine with more valence if you are of age and financially able to do so. However, it is important to note that HPV vaccination is not a permanent solution, and after vaccination, it is also important to pay attention to the prevention of sexually transmitted diseases and regular screening.