The pain in the middle of chest after sleeping may be caused by improper posture, mental factors, reflux esophagitis and other reasons. 1. Improper posture: If you sleep in an improper posture, the chest tissues are always compressed, resulting in poor local blood circulation or muscle spasms, so the phenomenon of pain in the middle of the chest after sleeping. 2. Mental factors: if the long-term mental tension, anxiety, depression of the people, may also appear in the middle of the chest pain in the sleep phenomenon. 3. Reflux esophagitis: when lying down to rest, due to the increase of gastric acid reflux, the stimulation of the esophagus may appear to sleep in the middle of the sternum burning pain, accompanied by acid reflux, heartburn and other symptoms. Sleeping in the middle of the chest pain in the patients, in the exclusion of physiological causes, should go to the regular hospital in time, clear cause, in the guidance of professional doctors for targeted treatment.