There are two main causes of stomach pain the day after drinking alcohol. The first cause may be caused by alcohol stimulating the mucosa of the gastrointestinal tract, which may be due to excessive alcohol consumption or the patient’s body intolerance to alcohol. The second reason may be caused by gastroenteritis, which is due to the fact that alcohol has certain lipophilic and lipolytic properties, and if it overstimulates the mucous membrane of the gastrointestinal tract, it will lead to inflammatory cell infiltration and cause gastroenteritis, and patients should go to the hospital as soon as possible after this situation to do relevant tests to clarify the diagnosis, and after the doctor’s diagnosis to treat the symptoms with symptomatic medication, which can usually take some painkillers and drugs to protect the gastric mucosa to relieve the symptoms. In addition to this, the next day after drinking alcohol stomach pain may also be caused by some liver and gallbladder disease or appendicitis, the patient after drinking alcohol will stimulate the inflammatory attack, so patients must go to the hospital as soon as possible after the onset of the disease, to clarify the cause and then symptomatic treatment.