Differential diagnosis of Ig and complement deposition in and around the vessel wall

Ig and complement deposition in and around the vessel wall is one of the symptoms of urticarial vasculitis urticarial vasculitis was first reported by MCDuffie in 1973 and is characterized by a rash that is windy and long-lasting with hypocomplementemia. Inflammatory mediators damage vascular endothelial cells and therefore vasculitic changes occur, showing signs of leukocytoclastic vasculitis. What are the symptoms that are easily confused with it? 1, chronic urticaria Chronic urticaria accounts for about 2/3 of urticaria, and the cluster occurs repeatedly, sometimes more and sometimes less, often over the years, up to 2 months or more. The symptoms are generally mild, and most patients cannot find the cause. Systemic lupus erythematosus (SLE) is an autoimmune disease that involves multiple systems and organs and has multiple autoantibodies. Tissue damage is caused by the presence of a large number of pathogenic autoantibodies and immune complexes in the body. Clinical manifestations may include damage to various systems and organs, such as the skin, joints, plasma membranes, heart, kidneys, central nervous system, and blood system. The disease occurs worldwide, with a prevalence of 4/100,000 to 25/100,000, with a higher prevalence in Asia and blacks, and a prevalence of 70/100,000 to 75/100,000 in China. The incidence is significantly higher in women than in men, about 10:1, with a peak in women of childbearing age, and in the elderly and children. The disease belongs to the category of yin and yang poison, yang poison hair spots, butterfly spots, sun sores, ghost face sores, face travel wind and other diseases in Chinese medicine. The etiology of the disease is unknown, with reports of hypersensitivity vasculitis caused by iodine allergy, repeated cold stimulation, and allergens such as viruses, bacteria, and parasites. Clinical blood tests can be divided into general blood tests, laboratory tests for hemolytic anemia, bone marrow cytology tests, blood group identification and cross-matching tests. Hematologic holding signs of common blood disorders can be detected.