The main glucose-lowering hormone in the human body is insulin, while growth hormone, cortisol, epinephrine, norepinephrine, glucagon, etc. Endocrine disorders cause increased secretion of the above hormones will cause diabetes. This type of diabetes belongs to the category of secondary diabetes mellitus, such as patients with acromegaly, pituitary growth hormone secretion will cause diabetes mellitus. patients with Cushing’s syndrome, because of a variety of reasons caused by the excessive secretion of adrenal cortisol, the patient will have elevated blood glucose. In addition, patients with pheochromocytoma have excessive secretion of epinephrine and norepinephrine by the adrenal glands, and patients with glucagonoma have excessive secretion of glucagon, all of which can cause diabetes mellitus. In hormone-induced diabetes, if the primary disease can be cured, most patients’ blood sugar can return to normal. Another common situation is that patients who use glucocorticoids for a long time and in high doses because of other diseases can also cause elevated blood sugar and diabetes. After stopping the drug, the blood sugar of some patients can also gradually return to normal.