Anal suppositories are usually inserted slowly into the anus after washing the fingers or wearing disposable sterile gloves, and after insertion the suppositories are usually kept in a prone or side-lying position to prevent slippage. Mainly used for the treatment of hemorrhoids, rectal inflammation and other diseases. Suppository refers to the drug and the appropriate matrix made of a certain shape for the body cavity for the administration of solid preparations. Suppositories are solid at room temperature, and after being inserted into the cavity, they can be softened and melted or dissolved in secretion fluid at body temperature, gradually releasing the drug to produce local or systemic effects. With suppositories, the drug is not or less damaged by gastrointestinal pH or enzymes, which is suitable for patients who cannot or do not want to take the drug orally. Intravenous absorption in the lower and middle rectum avoids hepatic first pass effects. The anal pessary is inserted into the anus, and after a while the drug is absorbed, the hands must be washed and sterilized in time to avoid bacterial or viral transmission. During the treatment period, we should abstain from spicy and stimulating food, quit smoking and avoid alcohol, exercise more and drink more water.