Genital herpes may still recur after circumcision. The cause of genital herpes is mainly herpes simplex virus type 2 (HSV-2) infection, which has no causal relationship with whether or not to cut the foreskin, and may still recur after circumcision. Genital herpes is a sexually transmitted disease that can easily develop around the penis and glans in men or at the cervix, vaginal opening and vulva in women, manifesting itself as papules, clustered blisters, etc., accompanied by localized skin and mucous membrane ulcers, vesicles, oozing, and so on. Genital herpes requires antiviral medication, which can be used topically, such as acyclovir ointment; in severe cases or recurrent cases, systemic antiviral medication, such as interferon, acyclovir, etc., as well as immunomodulators, such as thymopeptide, etc., are also used. The use of medication should follow the doctor’s instructions. Male genital herpes patients can be circumcised after healing, but the removal of the foreskin can not completely prevent the recurrence of the disease. Tiredness, alcohol consumption and other factors can trigger the recurrence of genital herpes. The key to preventing genital herpes is to maintain a healthy lifestyle, improve immunity and avoid unclean sex.