Blisters on the mouth (blisters) broken bleeding consider herpes simplex, hand, foot and mouth disease, lipitis, etc., the main treatment is drug therapy. 1. herpes simplex: herpes simplex is caused by the herpes simplex virus, which is somewhat contagious, and the main manifestation is clustered blisters. if it breaks and bleeds, it can be disinfected with local iodophor, and treated with antiviral medications such as oral acyclovir. 2. Hand, foot and mouth disease: this is caused by enterovirus infection, will be distributed in the hands, feet and mouth and other parts of the herpes, the disease can improve on its own, mild patients do not need special treatment, pay attention to cleaning and disinfection can be. 3. Lipitis: Lipitis is an inflammation that occurs in the lips, there will also be symptoms of blisters, you can use isacridine solution, saline for wet compresses, if it is allergic to cause blisters, you can also take chlorpheniramine maleate, loratadine and other antihistamine drugs. Blisters on the mouth broke bleeding to pay attention to local cleanliness and hygiene, the above medication should be used under the guidance of a doctor, avoid self-medication.