Tubular adenoma of the colon is a type of adenoma, which is a benign tumor, low-grade intraepithelial neoplasia to precancerous lesion, referring to heterogeneous hyperplasia involving <2/3 of the mucosa. Adenomas are common benign tumors of the gastrointestinal tract with a certain risk of malignancy, and can be divided into tubular adenomas, choriocarpous adenomas and mixed adenomas (with both tubular and chorioallantoic structures). The risk of malignancy of tubular adenomas is lower than that of chorioallantoic adenomas, and the bigger the tubular adenomas are, the higher the risk of malignancy. Heteroplasia is a localized lesion in which the proliferating cells are different from normal cells in terms of morphology, arrangement, and nuclear morphology. Intraepithelial neoplasia is a description of the process of heterogeneous hyperplasia to carcinoma in situ. Low-grade intraepithelial neoplasia, including mild and moderate heterogeneous hyperplasia, refers to the accumulation of heterogeneously proliferating cells in <2/3 layer of the mucosa. Generally, colonic tubular adenoma with low-grade intraepithelial neoplasia needs to be treated by mucosal resection or stripping under enteroscopy, and the resected tissue also needs to be routinely pathologically examined. It is recommended to consult the doctor in time and follow the doctor's instructions for examination and treatment.