Progesterone and chorionic gonadotropin, both are two of the more important hormones in early pregnancy. In patients with low progesterone and low HCG values, the probability of successful fertility preservation is very low and can easily lead to unavoidable miscarriage, and also to biochemical pregnancy. Low progesterone and low HCG usually indicate poor embryo viability, which means that the quality of the fertilized egg is not high. In this case, if the effect of fertility preservation is not good, it is recommended not to blindly continue to preserve the pregnancy, and it is better to terminate the pregnancy early. In addition, before the next pregnancy, it is recommended that the couple go to the Department of Eugenics and Genetics for a relevant examination to see if there are other factors that affect the probability of pregnancy, in addition to taking folic acid.