The respiratory system will show coughing, coughing phlegm, chest tightness, and even coughing blood; the blood system will cause anemia and decrease in white blood cells; the motor system will cause bone and joint pain and bone and joint effusion; the cardiovascular system will cause panic, palpitations, chest tightness, and pericardial effusion; the digestive system will cause loss of appetite, nausea, and vomiting. So often patients will have various symptoms of multi-system. If patients have multi-system damage, such as coughing, chest tightness, appearing anemia and joint pain, etc., it may often be a case of kidney function failure.