The use of B. burgdorferi vaccine should pay attention to personal protection, avoiding the use of antibiotics, pregnant animals prohibited, reasonable place to inject the vaccine apparatus, and so on. 1. Brucella vaccine is mainly used to prevent cattle and sheep from being infected with Brucella. B. burgdorferi has a certain pathogenicity to human body, when using it, we must pay attention to personal protection, wear gloves, masks, avoid direct contact with the vaccine. 2. B. burgdorferi vaccine is usually mixed with cool water for dunking livestock, and can also be mixed into the feed, but be sure to avoid combining with feed containing antibiotic additives, antibiotics may reduce the effect of B. burgdorferi vaccine. 3. Brucella vaccination is not suitable for pregnant animals. 4. Used vaccine bottles, syringes and unused vaccine should be sterilized after vaccination.