Combination of drugs in hypertensive patients can increase the antihypertensive effect without increasing the adverse effects, and two or more antihypertensive drugs are often used. Commonly used antihypertensive drugs are diuretics (such as hydrochlorothiazide), calcium channel receptor blockers (such as nifedipine), angiotensin-converting enzyme inhibitors (such as Benadryl), angiotensin II receptor antagonists (such as Irbesartan), β-receptor antagonists (such as metoprolol), the specific choice of which one to be used according to the condition of the disease and the doctor’s judgment of the use of medication, and comply with the doctor’s instructions. Hypertensive patients need to frequently monitor blood pressure, according to the blood pressure situation of the adjustment of drugs, under normal circumstances, antihypertensive drugs are generally taken in the morning on an empty stomach, often recommended to use calcium channel blockers (such as nifedipine, amlodipine benzenesulfonate tablets, etc.), but some people have high blood pressure in the afternoon or at night, you need to continue to take antihypertensive drugs in the afternoon or at night (such as Irbesartan, Benadryl, etc.). Such as uremia patients blood pressure is difficult to control, often recommended that patients take nifedipine in the morning and terazosin at night, which is typical of antihypertensive drugs to eat separately. Remember that high blood pressure medication needs to go to the hospital, find a doctor to adjust, can not change at will.