Tuberculosis is caused by infection of the lungs by Mycobacterium tuberculosis. When the organism is exposed to Mycobacterium tuberculosis, the development of TB is determined by both the bacteria and the host. The first is the number and virulence of the tubercle bacilli, and the second is the ability of the host to clear and limit infection with Mycobacterium tuberculosis. It is possible to come into contact with a person with TB who carries the bacteria in his sputum. TB patients spread it by expelling microdroplets containing Mycobacterium tuberculosis into the air by coughing, sneezing, laughing, and talking loudly. Immunocompromise: The host’s immune system is an important factor in inhibiting bacterial proliferation, and an impaired immune system can lead to the reactivation and proliferation of suppressed Mycobacterium tuberculosis. If you feel unwell