The need for long-term medication for subclinical hyperthyroidism needs to be evaluated by a medical professional. Generally, patients who are at a higher risk of developing hyperthyroidism may need to be treated with long-term medication for effective control of the condition. Subclinical hyperthyroidism is an abbreviation for subclinical hyperthyroidism, which is a more specific type of hyperthyroidism. Subclinical hyperthyroidism needs to be treated according to the level of thyroid stimulating hormone in the body as well as the age. For example, if the patient’s TSH is lower than the normal range but ≥0.1 mU/L, antithyroid therapy can be considered in the following cases: age ≥65 years old; combined with cardiac disease; and the clinical manifestation of hyperthyroidism. In conclusion, patients with subclinical hyperthyroidism should choose the appropriate treatment plan according to their actual condition and physical status. Individuals who are diagnosed with subclinical hyperthyroidism are advised to follow the doctor’s instructions for intervention.