The reasons why 45-year-old women don’t have menstruation are usually as follows: Firstly, 45-year-old women are in ovarian function decline, so it is possible that ovarian dysfunction caused by the lack of menstruation, at this time, we should pay attention to whether there are tumors of the ovary and uterine lesions. Secondly, 45-year-old women may also suffer from the decline of ovarian function, resulting in amenorrhea. Therefore, if a 45-year-old woman does not have her period, she should consider whether she has entered the menopause period and has amenorrhea. Thirdly, 45-year-old women also have occasional ovulation, so the lack of menstruation should also pay attention to whether it is pregnant, clinically should be given blood HCG measurement to rule out the possibility of pregnancy.