Itchy, red, swollen and peeling upper eyelid may be caused by neurodermatitis, atopic dermatitis or fungal infection. After clarifying the specific cause of the disease, it can be treated by symptomatic treatment with medications such as Dinocaprolactone cream, tacrolimus ointment, terbinafine cream and so on. 1. Neurodermatitis: generally related to the patient’s mental factors, in the long stay up late, stress, nervousness or repeated scratching will be more obvious. Patients can use Dinaid cream or tacrolimus ointment under the guidance of the doctor to improve. 2. Allergic dermatitis: After contacting or eating some kind of material allergy, redness, swelling and peeling with itching may also appear on the upper eyelid area. Tacrolimus ointment and pimecrolimus ointment can be used externally, and antihistamine drugs such as levocetirizine hydrochloride can be taken orally to improve the condition. 3. Fungal infection: localized fungal infection of the eyelid, there will be peeling, redness, swelling, itching, the patient can be used externally anti-fungal ointment, such as terbinafine cream, etc., if necessary, with oral itraconazole to improve. Itchy, swollen and peeling upper eyelid may have other reasons, it is recommended that the patient to the hospital in time to clarify the cause of the disease, follow the doctor’s instructions standardized treatment.