The clinical manifestations of acute suppurative meningitis can be divided into the following points:1, the onset of the disease is characterized by acute or explosive onset;2, the pre-symptomatic manifestations of fever, malignant cold, and upper respiratory tract infections;3, the patients with acute suppurative meningitis are positive for meningeal irritation sign, Kirschner’s sign, Brookings’s sign, and have symptoms of intracranial hypertension, such as headache, nausea, and vomiting;4, the acute suppurative meningitis affects the cerebral cortex, and the patients show symptoms such as seizures, palsy and other paralysis. Patients with acute suppurative meningitis affecting the cerebral cortex may have epilepsy and limb paralysis.