Liver echogenicity is one of the abnormal manifestations of liver ultrasound, which is common in fatty liver, chronic hepatitis, cirrhosis and so on. The color ultrasound alone shows that the liver echoes are dense and uniform, which can not make a definite diagnosis, and it is necessary to improve other related examinations and combine with clinical symptoms to make a comprehensive judgment. It is recommended that after the color ultrasound found that the liver echoes are dense and uniform, further testing of hepatitis B five, hepatitis C antibody, as well as liver function tests. The most common cause of liver echogenicity is fatty liver, but the diagnosis can only be made after exclusion of chronic hepatitis such as hepatitis B and C, exclusion of cirrhosis, and combination of blood lipid tests. When fat accumulates in the liver cells, fatty liver is formed, and thus the ultrasound will show the change of dense and homogeneous liver echogenicity. Therefore, patients with dense and homogeneous hepatic echoes should consult the doctor in time and follow the doctor’s instructions.