If you have drunk alcohol the day before the vaccination, it is recommended to reschedule the vaccination. If the vaccine has been injected, pay attention to observe whether the following adverse reactions exist: 1. Local symptoms: Pay attention to observe whether redness, swelling, oozing, hard nodules, pain, and itching occur at the vaccination site. This is because alcohol can promote blood circulation, dilate blood vessels and increase the permeability of blood vessels, increasing the chance of adverse reactions at the local injection site. If the above symptoms occur, but the symptoms are mild and not continuously aggravated, no special treatment is needed. Pay attention to not scratching with hands to prevent secondary bacterial infection. Generally 2-3 days, it can be cured naturally. If the above symptoms gradually worsen, you need to go to the hospital. 2. Systemic symptoms: pay attention to whether there is fever, headache, dizziness, weakness, etc. When the above symptoms appear, pay attention to bed rest, drink more water and ensure sleep. Generally, no special treatment is needed and it can recover on its own. 3. Gastrointestinal symptoms: pay attention to whether there are abdominal pain, diarrhea, nausea, vomiting and other gastrointestinal symptoms. Alcohol stimulates the mucous membrane of the gastrointestinal tract and can cause gastrointestinal dysfunction. Generally, no medication is needed. Pay attention to a light diet, and the symptoms will usually subside naturally in about 2-3 days. After vaccination, regardless of whether the above-mentioned discomfort occurs or other discomfort manifests itself, such as allergy, it is recommended to seek medical attention promptly if the symptoms are severe. If the symptoms are mild, take rest, drink more water, eat a light diet and avoid spicy and stimulating foods such as ginger, raw onion, chili, garlic and other stimulating condiments. Avoid seafood to prevent increasing the chances of allergy. In addition, pay attention to avoid strong tea and coffee to avoid affecting sleep.