Thyroid antibodies are self-produced immunoglobulins directed against the thyroid gland, and are clinically divided into two main categories: those directed against the surface of thyroid cells; and those directed against the contents of thyroid cells. The significance of checking the level of thyroid autoantibody titer is to understand the cause of thyroid disease, whether the autoimmune thyroid disease is still at its peak or the activity of the disease, as well as the indicators of adjusting medication, guiding the adjustment of medication and prognosis, suggesting that the patient is at risk of developing thyroid function problems in the future, and some of the antibodies can be used as a monitoring indicator of differentiated thyroid cancer, and the level of thyroid autoantibody is associated with thyroid disease. The level of thyroid autoantibodies is not directly related to the severity of thyroid disease.