The generic name of Gehua Zhi is metformin hydrochloride tablets, metformin extended-release tablets and metformin hydrochloride tablets are metformin glucose-lowering drugs, is a different dosage form of metformin, both of them have their own characteristics, there is no which one is better this statement, it is recommended to choose the drug under the guidance of the doctor. Metformin extended-release tablets and metformin hydrochloride tablets have the same main components, so there is no big difference in efficacy, side effects, contraindications, etc., the difference is mainly reflected in the drug dosage form. Metformin extended-release tablets are coated with thin-film technology, forming a thin film on the surface of the tablet to achieve the effect of slow release, so it is forbidden to chew orally to prevent damage to the film surface affecting the effect of slow release, and should be swallowed whole. Adverse effects of both include gastrointestinal discomfort, such as nausea, vomiting, diarrhea, abdominal pain, constipation, abdominal distension, as well as dizziness, headache, abnormal taste, muscle pain, hypotension, palpitations, rash, fatigue and so on. Contraindications include type 2 diabetes mellitus with ketoacidosis, hepatic and renal insufficiency, heart failure, acute myocardial infarction, severe infection and trauma, major surgery, presence of hypotension and hypoxia, previous history of lactic acidosis, and hypersensitivity to the product. Metformin Extended-Release Tablets and Metformin Hydrochloride Tablets should be taken under the supervision of a doctor and should not be taken on its own.