Patients with poor hepatic metabolism who have fever after taking medication and injections are more likely to consider drug fever or co-infections, where the treatment does not cover the causative organisms as well as the emergence of non-infectious fever. 1. Drug fever: most common in intravenous infusion of drugs, allergic reaction or exogenous pyrogen in the process of production, transportation or use of fever, after stopping the drug or applying anti-allergy treatment, fever symptoms gradually relieved. 2. Treatment does not cover the causative organisms: fever occurs after taking medication and injections, it may be that the current treatment is resistant or does not cover the causative organisms, or there are special pathogens such as fungi, tuberculosis, viruses that need to change the treatment program. 3. Fever in patients with poor liver function and metabolism after taking drugs and injections may also be non-infectious fever, such as blood system diseases, tumors, connective tissue disease and other reasons. It is recommended that patients with poor hepatic metabolism who have fever after taking medication and injections should consult a doctor in time, complete the relevant auxiliary examinations, and then treat the cause of the fever under the guidance of a specialist.