Pimples in medicine generally refers to acne, is a common dermatological chronic inflammatory follicular sebaceous gland disease, preferred in adolescent people, topical ointment mainly antibiotics and retinoids, such as clindamycin ointment, fusidic acid ointment, adapalene gel and so on. 1. Antibiotics: mainly for inflammatory acne, including pimples, pustular acne, such as fusidic acid ointment, clindamycin ointment, benzoyl peroxide gel, topical antibiotics can be used through the accumulation of drugs in the hair follicle to play an anti-inflammatory, killing Propionibacterium acnes. 2. Vitamin A acid: It is mainly suitable for acne-type pimples with mild inflammation, including blackhead pimples and whitehead pimples, such as Adapalene, Vitamin A acid and Tazarotene, etc., which can make the abnormal keratinization and clogged follicle pores reopened and open, and the sebum contents can be discharged easily, which is conducive to the elimination of acne-type pimples. It is recommended that acne patients use medication under the guidance of a professional dermatologist to avoid adverse reactions.