When a woman develops diabetes, it may affect her menstrual period, and in severe cases, she may be prone to amenorrhea. Diabetes mellitus is a typical endocrine metabolic disease, and the patient’s body is in a state of high blood sugar due to insulin deficiency and insulin resistance in the body. Insulin resistance also has an effect on the hormone secretion of the patient, such as sex hormones, progesterone, estrogen and so on. Women’s menstrual formation is related to progesterone and estrogen, and disorders of these two hormones may lead to irregular menstrual periods or even cause amenorrhea. There are also some diabetic patients who cause complications, such as autoimmune ovarian disease, which may affect a woman’s menstrual period due to higher cortisol secretion. Some diabetic patients are also overweight, and overweight can also lead to irregular menstruation. Therefore, diabetic patients should keep their blood glucose and weight within a reasonable range in order to avoid menstrual disorders. It is recommended that female patients in the treatment of diabetes, in addition to oral glucose-lowering drugs under the guidance of the doctor, but also symptomatic use of Dingkun Pills, female gold pills and other drugs to regulate the body.