Once gastric cancer is diagnosed by clinical pathology or imaging, it is generally malignant instead of benign. Whether malignant gastric cancer can be cured or not depends on the patient’s lesion, size, location and pathological stage, etc. For early carcinoma in situ and intramucosal gastric cancer, the prognosis of this kind of gastric cancer is relatively good if it can be detected and treated by surgery at an early stage. Some very early gastric cancers can be completely cured through gastroscopic intervention, but for middle or advanced gastric cancers, the curative effect is relatively poor. However, with the improvement of bio-targeted therapy, technology and medication, it is possible to improve the survival and cure rate of intermediate and advanced gastric cancer through surgical treatment and radiotherapy and chemotherapy at the same time. Therefore, patients with stomach cancer should not give up the treatment, and should actively adopt comprehensive programs to improve the cure rate.