New coronavirus infection is mainly characterized by respiratory symptoms such as a dry cough in the early stages of the infection, and nosebleeds are rare in the early stages of the infection. New coronavirus infection mainly violates the human respiratory system in the early stage, at this time may cause respiratory symptoms and systemic symptoms such as dry cough, fever, fatigue, muscle aches and pains, etc., clinically asymptomatic infected patients and light patients are more common. Some patients with severe or critical disease may develop respiratory distress as the disease progresses. For severe or critical patients with new coronavirus infection, the virus may involve the circulatory system, respiratory system, and blood system, leading to respiratory distress syndrome, sepsis, and coagulation dysfunction. At this time, the body may have nosebleeds due to abnormal coagulation function. Normally, nosebleeds do not occur in the early stage of new coronavirus infection or in mild cases of new coronavirus infection, but the possibility of very special cases cannot be ruled out, and timely examination and treatment are recommended.