Liver transplantation requires a decision on how many years to live based on the primary pathology and the presence of complications after transplantation, with the longest liver transplant life span reaching more than twenty years. If the liver transplant is for simple cirrhosis, benign liver disease, and there are no complications such as bile leaks, gastrointestinal bleeding, or biliary strictures after the liver transplant, the patient’s life expectancy is basically unaffected. If the patient’s primary disease for liver transplantation becomes a liver tumor, bile duct cell carcinoma or is considered to be another malignant tumor of the liver, the nature and biology of the primary tumor will need to be determined, and generally rarely exceeds five years after liver transplantation. In the case of patients with liver malignancy or other tumors that develop immune rejection or other complications after transplantation, including gastrointestinal hemorrhage and bile duct wall stenosis, the life expectancy is significantly reduced and may generally be between six months and one year. However, most patients with liver transplantation do not have a high chance of complications and can live up to 5-10 years, even for malignant tumors.