Knee joint pain caused by high uric acid is still mainly caused by acute inflammation, and this condition should belong to the acute arthritic attack of gout. If the knee is obviously swollen and painful, you can apply joint puncture and local injection of glucocorticoids to quickly reduce swelling and pain, and also combine with other anti-inflammatory drugs for treatment, such as colchicine, or etoricoxib tablets, both of which have the effect of reducing swelling, analgesia, anti-inflammation and antipyretic, and you can also apply cold compresses locally to relieve symptoms. After the condition is relieved, reasonable uric acid-lowering drugs should be applied for treatment, and complications should be actively prevented, and relapse should be prevented, such as febuxostat, allopurinol, and benzbromarone. Patients should improve their poor living habits and diet, and review the relevant indicators regularly.