Cirrhosis does not necessarily have nodules. If cirrhosis is in its early stages, the liver may be free of nodules. Cirrhosis is caused by hepatitis B virus infection, parasitic infection, alcohol, cholestasis, liver blood circulation disorders, genetic and metabolic diseases and other factors, resulting in extensive necrosis of liver cells, diffuse proliferation of fibrous connective tissue in the liver, based on which the formation of nodules, pseudofollicles and other abnormal structures, which leads to the destruction of the normal structure and blood supply of the liver. In the early stage of cirrhosis, although there is proliferation of fibrous tissue, but not yet produced nodules and pseudo lobe, etc. At this time, the liver function can still be compensated for, there may be no varicose veins, ascites, hemorrhage, and other symptoms, or even no symptoms, or occasional loss of appetite, fatigue, diarrhea, and other non-specific manifestations. Cirrhosis patients are advised to seek medical treatment in time to make a clear diagnosis, and carry out targeted treatment under the guidance of the doctor, do not delay, so as not to aggravate the condition.