The first-line treatments recommended for psychotherapy are cognitive behavioral therapy, systematic desensitization therapy, humanistic therapy, and psychoanalytic therapy. If one’s cleanliness is serious because of inner sensitivity, low self-esteem or inability to accept oneself, so that there are problems such as repeated checks and the pursuit of cleanliness, one can consider humanistic therapy to learn to accept oneself and learn to grow. If you have a lot of contradictions and conflicts in your subconscious, you can also consider psychoanalytic therapy to solve them. In terms of medication, you can consider using some anti-compulsive and anti-anxiety drugs, such as fluoxetine, paroxetine, fluvoxamine, clomipramine, etc., which are very effective and will generally improve significantly in about 4-8 weeks of taking the medication. When you are always in the trouble of cleanliness, you should do things that can make you happy, such as listening to music, watching movies, reading world famous books, etc., so that you can devote your attention to things you like, so that you can become fulfilled and happy. At the same time, you can also actively seek the support and understanding of friends and family members, only a combination of these methods can effectively solve the problem.